Assay

PGDB_AS001132

System: cell_basedTarget: IKZF2
Assay context summary

Assay context

6 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF2
E3Not specified
OrganismHomo sapiens
Technologyflow_cytometry
Detection targetprotein_degradation
Activity compounds and values

Activity records

6 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C010127
DC50-=247nM-—IKZF2--WO2025049840PGDB_A010425PGDB_C010127PGDB_AS001132View
2D structure for PGDB_C010125
DC50-=45nM-—IKZF2--WO2025049840PGDB_A027053PGDB_C010125PGDB_AS001132View
2D structure for PGDB_C007373
DC50->1000nM-—IKZF2--WO2025049840PGDB_A047098PGDB_C007373PGDB_AS001132View
2D structure for PGDB_C010126
DC50-=205nM-—IKZF2--WO2025049840PGDB_A048936PGDB_C010126PGDB_AS001132View
2D structure for PGDB_C007372
DC50->1000nM-—IKZF2--WO2025049840PGDB_A052723PGDB_C007372PGDB_AS001132View
2D structure for PGDB_C010128
DC50-=155nM-—IKZF2--WO2025049840PGDB_A075600PGDB_C010128PGDB_AS001132View
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