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Compound
PGDB_C002556
8 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CC3(CN(Cc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)C3)C2)=C(c2ccc(F)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A007712 | PGDB_C002556 | PGDB_AS002239 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A037392 | PGDB_C002556 | PGDB_AS000668 | View |
| IC50 | - | = | 0.56 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A042059 | PGDB_C002556 | PGDB_AS000095 | View |
| IC50 | - | = | 100-500 | nM | - | — | - | - | Daudi | WO2024032689A1 | PGDB_A043043 | PGDB_C002556 | PGDB_AS002481 | View |
| IC50 | - | = | 10-50 | nM | - | — | - | - | MM.1S | WO2024032689A1 | PGDB_A047158 | PGDB_C002556 | PGDB_AS001703 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A049627 | PGDB_C002556 | PGDB_AS000176 | View |
| IC50 | - | = | 10-50 | nM | - | — | - | - | CCRF-CEM | WO2024032689A1 | PGDB_A051914 | PGDB_C002556 | PGDB_AS001396 | View |
| IC50 | - | = | 10-50 | nM | - | — | - | - | Mino | WO2024032689A1 | PGDB_A059355 | PGDB_C002556 | PGDB_AS001319 | View |