Summary
AssigneeC4 Therapeutics
Filing years2018-2022
Patents8
Compounds595
Activity records917
Patent families8
Targets6
Assay familiesbinding, biochemical, degradation, viability
Activity metricsDC50, Emax, GI50, IC50, Kd
Overview

Target distribution and active-compound trend

Target distribution

917 activity records

6 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

0109217201920202021202320242025
Activity compounds and values

Activity records

917 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C016642
Emax-=60-95%--GSPT1-293T.114AU2021361043A9PGDB_A008798PGDB_C016642PGDB_AS000916View
2D structure for PGDB_C019158
Emax-=60-95%--IKZF2-JURKAT.21AU2021361043A9PGDB_A009073PGDB_C019158PGDB_AS001733View
2D structure for PGDB_C016640
Emax-=60-95%--IKZF2--AU2021361043A9PGDB_A009186PGDB_C016640PGDB_AS000275View
2D structure for PGDB_C019167
Emax-=60-95%--IKZF2-JURKAT.21AU2021361043A9PGDB_A009903PGDB_C019167PGDB_AS001733View
2D structure for PGDB_C019162
Emax-=60-95%--GSPT1-293T.114AU2021361043A9PGDB_A010699PGDB_C019162PGDB_AS000916View
2D structure for PGDB_C019154
Emax->95%--GSPT1-293T.114AU2021361043A9PGDB_A011049PGDB_C019154PGDB_AS000916View
2D structure for PGDB_C019170
DC50->10000nM-IKZF2-JURKAT.21AU2021361043A9PGDB_A012031PGDB_C019170PGDB_AS000724View
2D structure for PGDB_C016643
Emax-=60-95%--IKZF2-JURKAT.21AU2021361043A9PGDB_A012609PGDB_C016643PGDB_AS001733View
2D structure for PGDB_C019171
DC50->10000nM-IKZF2-JURKAT.21AU2021361043A9PGDB_A012677PGDB_C019171PGDB_AS000724View
2D structure for PGDB_C016651
Emax-=60-95%--IKZF2-JURKAT.21AU2021361043A9PGDB_A012775PGDB_C016651PGDB_AS001733View
2D structure for PGDB_C019156
DC50->10000nM-IKZF2-JURKAT.21AU2021361043A9PGDB_A013192PGDB_C019156PGDB_AS000724View
2D structure for PGDB_C016640
Emax->95%--IKZF2--AU2021361043A9PGDB_A014355PGDB_C016640PGDB_AS000347View
2D structure for PGDB_C019157
Emax-=60-95%--IKZF2-JURKAT.21AU2021361043A9PGDB_A015038PGDB_C019157PGDB_AS001733View
2D structure for PGDB_C019152
DC50->10000nM-IKZF2-JURKAT.21AU2021361043A9PGDB_A015246PGDB_C019152PGDB_AS000724View
2D structure for PGDB_C019164
Emax-=60-95%--IKZF2-JURKAT.21AU2021361043A9PGDB_A015467PGDB_C019164PGDB_AS001733View
2D structure for PGDB_C016651
DC50->10000nM-IKZF2-JURKAT.21AU2021361043A9PGDB_A015772PGDB_C016651PGDB_AS000724View
2D structure for PGDB_C016642
Emax-<45%--IKZF2--AU2021361043A9PGDB_A016404PGDB_C016642PGDB_AS000275View
2D structure for PGDB_C019161
DC50->10000nM-GSPT1-293T.114AU2021361043A9PGDB_A016417PGDB_C019161PGDB_AS002445View
2D structure for PGDB_C019152
Emax-=60-95%--IKZF2-JURKAT.21AU2021361043A9PGDB_A017454PGDB_C019152PGDB_AS001733View
2D structure for PGDB_C019154
DC50->10000nM-IKZF2-JURKAT.21AU2021361043A9PGDB_A019727PGDB_C019154PGDB_AS000724View