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Compound
PGDB_C016651
8 activity records2 related patents
2D structure
CC(NC(=O)c1ccc2c3c(ccnc13)N(C1CCC(=O)NC1=O)C2=O)c1ccccc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | = | 60-95 | % | 10 uM | DC50 > 10000 nM | IKZF2 | - | JURKAT.21 | AU2021361043A9 | PGDB_A012775 | PGDB_C016651 | PGDB_AS001733 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | > 100 nM | DC50 < 100 nM | - | - | 293T.114 | WO2022081927A1 | PGDB_A015247 | PGDB_C016651 | PGDB_AS000287 | View |
| DC50 | - | > | 10000 | nM | - | — | IKZF2 | - | JURKAT.21 | AU2021361043A9 | PGDB_A015772 | PGDB_C016651 | PGDB_AS000724 | View |
| Emax | - | < | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM | - | - | KELLY.2 | WO2022081927A1 | PGDB_A020113 | PGDB_C016651 | PGDB_AS000499 | View |
| DC50 | - | < | 100 | nM | - | — | - | - | KELLY.2 | WO2022081927A1 | PGDB_A020685 | PGDB_C016651 | PGDB_AS001296 | View |
| DC50 | - | > | 10000 | nM | - | — | GSPT1 | - | 293T.114 | AU2021361043A9 | PGDB_A034237 | PGDB_C016651 | PGDB_AS002445 | View |
| DC50 | - | > | 100 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A041326 | PGDB_C016651 | PGDB_AS001223 | View |
| Emax | - | = | 60-95 | % | 10 uM | DC50 > 10000 nM | GSPT1 | - | 293T.114 | AU2021361043A9 | PGDB_A073996 | PGDB_C016651 | PGDB_AS000916 | View |