Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C016643
8 activity records2 related patents
2D structure
CN1CC(c2ccc3c4c(cccc24)N(C2CCC(=O)NC2=O)C3=O)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | = | 60-95 | % | 10 uM | DC50 > 10000 nM | IKZF2 | - | JURKAT.21 | AU2021361043A9 | PGDB_A012609 | PGDB_C016643 | PGDB_AS001733 | View |
| DC50 | - | > | 100 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A016760 | PGDB_C016643 | PGDB_AS001223 | View |
| DC50 | - | < | 100 | nM | - | — | - | - | KELLY.2 | WO2022081927A1 | PGDB_A043792 | PGDB_C016643 | PGDB_AS001296 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | > 100 nM | DC50 < 100 nM | - | - | 293T.114 | WO2022081927A1 | PGDB_A050779 | PGDB_C016643 | PGDB_AS000287 | View |
| DC50 | - | > | 10000 | nM | - | — | GSPT1 | - | 293T.114 | AU2021361043A9 | PGDB_A055223 | PGDB_C016643 | PGDB_AS002445 | View |
| Emax | - | = | 60-95 | % | 10 uM | DC50 > 10000 nM | GSPT1 | - | 293T.114 | AU2021361043A9 | PGDB_A062195 | PGDB_C016643 | PGDB_AS000916 | View |
| Emax | - | < | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM | - | - | KELLY.2 | WO2022081927A1 | PGDB_A071167 | PGDB_C016643 | PGDB_AS000499 | View |
| DC50 | - | > | 10000 | nM | - | — | IKZF2 | - | JURKAT.21 | AU2021361043A9 | PGDB_A072349 | PGDB_C016643 | PGDB_AS000724 | View |