Summary
AssigneeMinghui Pharmaceutical Shanghai
Filing years2022
Patents1
Compounds8
Activity records18
Patent families1
Targets1
Assay familiescellular_function, degradation, viability
Activity metricsGI50, IC50
Overview

Target distribution and active-compound trend

Target distribution

18 activity records

1 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

0482022
Activity compounds and values

Activity records

18 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C006617
IC50-=5.2nM-ESR1-HEK293CN115260206APGDB_A008502PGDB_C006617PGDB_AS000727View
2D structure for PGDB_C006617
IC50-=0.36nM-ESR1-MCF-7CN115260206APGDB_A008610PGDB_C006617PGDB_AS001594View
2D structure for PGDB_C006615
IC50-=10.1nM-ESR1-HEK293CN115260206APGDB_A010851PGDB_C006615PGDB_AS000727View
2D structure for PGDB_C006613
IC50-=8.7nM-ESR1-HEK293CN115260206APGDB_A014817PGDB_C006613PGDB_AS000727View
2D structure for PGDB_C006618
IC50-=0.18nM-ESR1-MCF-7CN115260206APGDB_A021093PGDB_C006618PGDB_AS001594View
2D structure for PGDB_C006613
IC50-=0.89nM-ESR1-MCF-7CN115260206APGDB_A022645PGDB_C006613PGDB_AS001594View
2D structure for PGDB_C006618
GI50-=0.1nM-ESR1-MCF-7CN115260206APGDB_A023365PGDB_C006618PGDB_AS001900View
2D structure for PGDB_C006620
IC50-=14.5nM-ESR1-HEK293CN115260206APGDB_A030709PGDB_C006620PGDB_AS000727View
2D structure for PGDB_C006614
IC50-=0.69nM-ESR1-MCF-7CN115260206APGDB_A030883PGDB_C006614PGDB_AS001594View
2D structure for PGDB_C006619
IC50-=1.5nM-ESR1-MCF-7CN115260206APGDB_A038756PGDB_C006619PGDB_AS001594View
2D structure for PGDB_C006614
IC50-=9.1nM-ESR1-HEK293CN115260206APGDB_A039781PGDB_C006614PGDB_AS000727View
2D structure for PGDB_C006616
IC50-=1nM-ESR1-MCF-7CN115260206APGDB_A051669PGDB_C006616PGDB_AS001594View
2D structure for PGDB_C006618
IC50-=4.9nM-ESR1-HEK293CN115260206APGDB_A052245PGDB_C006618PGDB_AS000727View
2D structure for PGDB_C006620
GI50-=0.24nM-ESR1-MCF-7CN115260206APGDB_A055381PGDB_C006620PGDB_AS001900View
2D structure for PGDB_C006619
IC50-=13.2nM-ESR1-HEK293CN115260206APGDB_A065365PGDB_C006619PGDB_AS000727View
2D structure for PGDB_C006620
IC50-=0.32nM-ESR1-MCF-7CN115260206APGDB_A066766PGDB_C006620PGDB_AS001594View
2D structure for PGDB_C006615
IC50-=1.1nM-ESR1-MCF-7CN115260206APGDB_A068762PGDB_C006615PGDB_AS001594View
2D structure for PGDB_C006616
IC50-=7.3nM-ESR1-HEK293CN115260206APGDB_A074912PGDB_C006616PGDB_AS000727View