PatGlueDB | Molecular Glue Patent Bioactivity Database

Activity compounds and values

Activity records

3,508 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
IC50	-	>	1900	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A007192	PGDB_C009949	PGDB_AS000845	View
DC50	-	>	300	nM	-	—	GSPT1	-	CAL-51	WO2022219407A1	PGDB_A007196	PGDB_C009979	PGDB_AS002523	View
IC50	-	>	1900	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A007717	PGDB_C009943	PGDB_AS000845	View
IC50	-	>	1000	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A008885	PGDB_C009973	PGDB_AS000712	View
DC50	-	<=	30	nM	-	—	GSPT1	-	CAL-51	WO2022219407A1	PGDB_A009177	PGDB_C009951	PGDB_AS002523	View
IC50	-	<=	600	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A009800	PGDB_C009920	PGDB_AS000845	View
IC50	-	>	1900	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A010119	PGDB_C009908	PGDB_AS000845	View
IC50	-	=	600-1200	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A011008	PGDB_C009913	PGDB_AS000845	View
IC50	-	=	1200-1900	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A011126	PGDB_C009945	PGDB_AS000845	View
DC50	-	<=	30	nM	-	—	GSPT1	-	CAL-51	WO2022219407A1	PGDB_A012726	PGDB_C009915	PGDB_AS002523	View
IC50	-	=	1200-1900	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A013006	PGDB_C009942	PGDB_AS000845	View
IC50	-	>	1900	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A013360	PGDB_C009940	PGDB_AS000845	View
DC50	-	=	30-300	nM	-	—	GSPT1	-	CAL-51	WO2022219407A1	PGDB_A013769	PGDB_C009909	PGDB_AS002523	View
IC50	-	<=	600	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A014224	PGDB_C009962	PGDB_AS000845	View
DC50	-	<=	30	nM	-	—	GSPT1	-	CAL-51	WO2022219407A1	PGDB_A014594	PGDB_C009931	PGDB_AS002523	View
DC50	-	<=	30	nM	-	—	GSPT1	-	CAL-51	WO2022219407A1	PGDB_A014681	PGDB_C009922	PGDB_AS002523	View
DC50	-	=	30-300	nM	-	—	GSPT1	-	CAL-51	WO2022219407A1	PGDB_A015089	PGDB_C009928	PGDB_AS002523	View
DC50	-	=	30-300	nM	-	—	GSPT1	-	CAL-51	WO2022219407A1	PGDB_A015610	PGDB_C009949	PGDB_AS002523	View
IC50	-	=	1200-1900	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A015848	PGDB_C009955	PGDB_AS000845	View
IC50	-	<=	600	nM	-	—	CRBN	CRBN	-	WO2022219407A1	PGDB_A015868	PGDB_C009914	PGDB_AS000845	View

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Monte Rosa Therapeutics

Target distribution and active-compound trend

Target distribution

Active compounds by publication year

Activity records