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O=C1CCC(N2Cc3ccc(COC(=O)Nc4nc5ccccc5s4)cc3C2=O)C(=O)N1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 119.97 | nM | - | — | CRBN | CRBN | - | CN118852145A | PGDB_A018386 | PGDB_C001471 | PGDB_AS000570 | View | |
| Dmax | - | = | 91.05 | % | Concentration series: 1 uM | 24 h | GSPT1 | - | HEK293 | CN118852145A | PGDB_A031982 | PGDB_C001471 | PGDB_AS002339 | View | |
| DC50 | - | = | 3.24 | nM | - | — | GSPT1 | - | HEK293 | CN118852145A | PGDB_A043485 | PGDB_C001471 | PGDB_AS001853 | View | |
| IC50 | - | = | 5.3 | nM | - | — | GSPT1 | - | NCI-H1155 | CN118852145A | PGDB_A043770 | PGDB_C001471 | PGDB_AS001039 | View |