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Compound
PGDB_C002508
9 activity records1 related patents
2D structure
O=C1CCC(N2C(=O)c3ccc(CN4CCN(Cc5ccccc5-c5ccc(Cl)cc5)CC4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A030568 | PGDB_C002508 | PGDB_AS000176 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A033255 | PGDB_C002508 | PGDB_AS002239 | View |
| IC50 | - | = | 100-500 | nM | - | — | - | - | MM.1S | WO2024032689A1 | PGDB_A033691 | PGDB_C002508 | PGDB_AS001703 | View |
| IC50 | - | = | 100-500 | nM | - | — | - | - | Kasumi-1 | WO2024032689A1 | PGDB_A037649 | PGDB_C002508 | PGDB_AS001291 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A041582 | PGDB_C002508 | PGDB_AS000668 | View |
| IC50 | - | = | 100-500 | nM | - | — | - | - | MV-4-11 | WO2024032689A1 | PGDB_A046921 | PGDB_C002508 | PGDB_AS000885 | View |
| IC50 | - | = | 50-100 | nM | - | — | - | - | CCRF-CEM | WO2024032689A1 | PGDB_A048875 | PGDB_C002508 | PGDB_AS001396 | View |
| IC50 | - | = | 100-500 | nM | - | — | - | - | Mino | WO2024032689A1 | PGDB_A049162 | PGDB_C002508 | PGDB_AS001319 | View |
| IC50 | - | = | 500-1000 | nM | - | — | - | - | Daudi | WO2024032689A1 | PGDB_A074274 | PGDB_C002508 | PGDB_AS002481 | View |