Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C006578
5 activity records1 related patents
2D structure
CC(C)c1cnn2c(NCc3cn4cc(F)ccc4n3)cc(NC[C@H]3CCNC[C@@H]3O)nc12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 168 | nM | - | — | CDK7 | - | - | CN114929708B | PGDB_A013923 | PGDB_C006578 | PGDB_AS002150 | View |
| IC50 | - | = | 33 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A022914 | PGDB_C006578 | PGDB_AS001187 | View |
| Selectivity index | CDK7 / CDK12 | = | 5.1 | fold | - | — | - | - | - | CN114929708B | PGDB_A041219 | PGDB_C006578 | PGDB_AS002236 | View |
| IC50 | - | = | 33 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A070263 | PGDB_C006578 | PGDB_AS001268 | View |
| IC50 | - | = | 6.3 | nM | - | — | CDK12 | - | A673 | CN114929708B | PGDB_A075449 | PGDB_C006578 | PGDB_AS002570 | View |