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Compound
PGDB_C006582
5 activity records1 related patents
2D structure
Cc1ccn2c(CNc3cc(NC[C@H]4CCNC[C@@H]4O)nc4c(C(C)C)cnn34)c(C)nc2c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 277 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A014945 | PGDB_C006582 | PGDB_AS001268 | View |
| IC50 | - | = | 3 | nM | - | — | CDK7 | - | - | CN114929708B | PGDB_A019504 | PGDB_C006582 | PGDB_AS002150 | View |
| Selectivity index | CDK7 / CDK12 | = | 0.01 | fold | - | — | - | - | - | CN114929708B | PGDB_A028683 | PGDB_C006582 | PGDB_AS002236 | View |
| IC50 | - | = | 277 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A030984 | PGDB_C006582 | PGDB_AS001187 | View |
| IC50 | - | = | 151 | nM | - | — | CDK12 | - | A673 | CN114929708B | PGDB_A058929 | PGDB_C006582 | PGDB_AS002570 | View |