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Compound
PGDB_C006585
5 activity records1 related patents
2D structure
[2H]C([2H])(Nc1cc(NC[C@H]2CCNC[C@@H]2O)nc2c(C(C)C)cnn12)c1cn2ccccc2n1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 65 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A014165 | PGDB_C006585 | PGDB_AS001268 | View |
| IC50 | - | = | 206 | nM | - | — | CDK7 | - | - | CN114929708B | PGDB_A019767 | PGDB_C006585 | PGDB_AS002150 | View |
| IC50 | - | = | 65 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A027574 | PGDB_C006585 | PGDB_AS001187 | View |
| IC50 | - | = | 16.3 | nM | - | — | CDK12 | - | A673 | CN114929708B | PGDB_A049255 | PGDB_C006585 | PGDB_AS002570 | View |
| Selectivity index | CDK7 / CDK12 | = | 3.2 | fold | - | — | - | - | - | CN114929708B | PGDB_A054577 | PGDB_C006585 | PGDB_AS002236 | View |