Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C006588
5 activity records1 related patents
2D structure
CC(C)c1cnn2c(NCc3cnc4ccccc4c3)cc(NC[C@H]3CCNC[C@@H]3O)nc12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selectivity index | CDK7 / CDK12 | = | 0.2 | fold | - | — | - | - | - | CN114929708B | PGDB_A021158 | PGDB_C006588 | PGDB_AS002236 | View |
| IC50 | - | = | 28 | nM | - | — | CDK7 | - | - | CN114929708B | PGDB_A023093 | PGDB_C006588 | PGDB_AS002150 | View |
| IC50 | - | = | 167 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A063966 | PGDB_C006588 | PGDB_AS001187 | View |
| IC50 | - | = | 167 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A068651 | PGDB_C006588 | PGDB_AS001268 | View |
| IC50 | - | = | 2.7 | nM | - | — | CDK12 | - | A673 | CN114929708B | PGDB_A076335 | PGDB_C006588 | PGDB_AS002570 | View |