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Compound
PGDB_C006603
5 activity records1 related patents
2D structure
Cn1c(CNc2cc(NC[C@H]3CCNC[C@@H]3O)nc3c(C4CC4)cnn23)nc2cc(F)c(F)cc21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 10.4 | nM | - | — | CDK12 | - | A673 | CN114929708B | PGDB_A033974 | PGDB_C006603 | PGDB_AS002570 | View |
| IC50 | - | = | 1150 | nM | - | — | CDK7 | - | - | CN114929708B | PGDB_A039019 | PGDB_C006603 | PGDB_AS002150 | View |
| Selectivity index | CDK7 / CDK12 | = | 4 | fold | - | — | - | - | - | CN114929708B | PGDB_A040206 | PGDB_C006603 | PGDB_AS002236 | View |
| IC50 | - | = | 287 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A043223 | PGDB_C006603 | PGDB_AS001187 | View |
| IC50 | - | = | 287 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A075599 | PGDB_C006603 | PGDB_AS001268 | View |