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Compound
PGDB_C007940
5 activity records1 related patents
2D structure
Cc1nc(C)c(COC(=O)NCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)s1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.44 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A029984 | PGDB_C007940 | PGDB_AS001908 | View |
| Dmax | - | = | 22 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A048865 | PGDB_C007940 | PGDB_AS001468 | View |
| IC50 | - | = | 0.26 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A050255 | PGDB_C007940 | PGDB_AS002309 | View |
| IC50 | - | = | 0.52 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A061405 | PGDB_C007940 | PGDB_AS002528 | View |
| Dmax | - | = | 23 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A065367 | PGDB_C007940 | PGDB_AS002435 | View |