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Compound
PGDB_C007941
5 activity records1 related patents
2D structure
Cc1nc(-c2ccccc2)sc1COC(=O)NCc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.084 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A007254 | PGDB_C007941 | PGDB_AS001908 | View |
| IC50 | - | = | 0.086 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A024593 | PGDB_C007941 | PGDB_AS002528 | View |
| Dmax | - | = | 22 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A024969 | PGDB_C007941 | PGDB_AS002435 | View |
| Dmax | - | = | 24 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A026678 | PGDB_C007941 | PGDB_AS001468 | View |
| IC50 | - | = | 0.16 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A033591 | PGDB_C007941 | PGDB_AS002309 | View |