Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C007943
5 activity records1 related patents
2D structure
Cc1nc2cc(COC(=O)NCc3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4)ccc2s1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.079 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A009413 | PGDB_C007943 | PGDB_AS002309 | View |
| IC50 | - | = | 0.064 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A026953 | PGDB_C007943 | PGDB_AS002528 | View |
| Dmax | - | = | 24 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A039489 | PGDB_C007943 | PGDB_AS002435 | View |
| Dmax | - | = | 24 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A058546 | PGDB_C007943 | PGDB_AS001468 | View |
| IC50 | - | = | 0.031 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A064030 | PGDB_C007943 | PGDB_AS001908 | View |