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Compound
PGDB_C007981
5 activity records1 related patents
2D structure
CC1(C)CCc2nc(COC(=O)NCc3cc(Cl)c4c(c3F)C(=O)N(C3CCC(=O)NC3=O)C4)sc2C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 79 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A009633 | PGDB_C007981 | PGDB_AS000677 | View |
| Dmax | - | = | 5 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A016422 | PGDB_C007981 | PGDB_AS000429 | View |
| IC50 | - | = | 0.0062 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A017762 | PGDB_C007981 | PGDB_AS001302 | View |
| IC50 | - | = | 10 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A024580 | PGDB_C007981 | PGDB_AS002511 | View |
| Kd | - | = | 0.016 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A067766 | PGDB_C007981 | PGDB_AS000368 | View |