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Compound
PGDB_C007996
5 activity records1 related patents
2D structure
CC1CCCc2nnc(COC(=O)NCc3cc(Cl)c4c(c3F)C(=O)N(C3CCC(=O)NC3=O)C4)cc21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kd | - | = | 0.35 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A011604 | PGDB_C007996 | PGDB_AS000368 | View |
| Dmax | - | = | 70 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A011631 | PGDB_C007996 | PGDB_AS000677 | View |
| IC50 | - | = | 0.046 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A031865 | PGDB_C007996 | PGDB_AS001302 | View |
| Dmax | - | = | 1.9 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A047086 | PGDB_C007996 | PGDB_AS000429 | View |
| IC50 | - | = | 10 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A072947 | PGDB_C007996 | PGDB_AS002511 | View |