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Compound
PGDB_C008001
5 activity records1 related patents
2D structure
Cc1cc(COC(=O)NCc2cc(Cl)c3c(c2F)C(=O)N(C2CCC(=O)NC2=O)C3)nn1C1CCC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.012 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A014451 | PGDB_C008001 | PGDB_AS001302 | View |
| Kd | - | = | 0.045 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A022452 | PGDB_C008001 | PGDB_AS000368 | View |
| IC50 | - | = | 10 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A036098 | PGDB_C008001 | PGDB_AS002511 | View |
| Dmax | - | = | 5.7 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A046109 | PGDB_C008001 | PGDB_AS000429 | View |
| Dmax | - | = | 75 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A062570 | PGDB_C008001 | PGDB_AS000677 | View |