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Compound
PGDB_C008007
5 activity records1 related patents
2D structure
Cc1cc(CNC(=O)OCc2cc3n(n2)CCCC3)c(F)c2c1CN(C1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 66 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A022397 | PGDB_C008007 | PGDB_AS000677 | View |
| IC50 | - | = | 0.023 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A041531 | PGDB_C008007 | PGDB_AS001302 | View |
| IC50 | - | = | 1 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A055753 | PGDB_C008007 | PGDB_AS002511 | View |
| Dmax | - | = | 3.8 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A056591 | PGDB_C008007 | PGDB_AS000429 | View |
| Kd | - | = | 0.37 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A060057 | PGDB_C008007 | PGDB_AS000368 | View |