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Compound
PGDB_C008015
5 activity records1 related patents
2D structure
CC1(C)OCCn2nc(COC(=O)NCc3cc(Cl)c4c(c3F)C(=O)N(C3CCC(=O)NC3=O)C4)cc21Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 1.4 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A019503 | PGDB_C008015 | PGDB_AS000429 | View |
| Kd | - | = | 0.13 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A020393 | PGDB_C008015 | PGDB_AS000368 | View |
| Dmax | - | = | 69 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A023089 | PGDB_C008015 | PGDB_AS000677 | View |
| IC50 | - | = | 1 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A027118 | PGDB_C008015 | PGDB_AS002511 | View |
| IC50 | - | = | 0.064 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A050165 | PGDB_C008015 | PGDB_AS001302 | View |