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Compound
PGDB_C008028
5 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(CNC(=O)OC4CC(c5cc(F)cc(F)c5)C4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 39 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A008964 | PGDB_C008028 | PGDB_AS000735 | View |
| IC50 | - | = | 0.051 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A053456 | PGDB_C008028 | PGDB_AS000958 | View |
| IC50 | - | = | 0.089 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A069063 | PGDB_C008028 | PGDB_AS000366 | View |
| Dmax | - | = | 41 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A070384 | PGDB_C008028 | PGDB_AS002240 | View |
| IC50 | - | = | 0.092 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A077583 | PGDB_C008028 | PGDB_AS002405 | View |