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Compound
PGDB_C008029
6 activity records1 related patents
2D structure
COc1ccccc1C1CC(OC(=O)NCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 40 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A007954 | PGDB_C008029 | PGDB_AS000735 | View |
| IC50 | - | = | 0.025 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A009839 | PGDB_C008029 | PGDB_AS000366 | View |
| Dmax | - | = | 40 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A013022 | PGDB_C008029 | PGDB_AS002240 | View |
| IC50 | - | = | 0.032 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A016200 | PGDB_C008029 | PGDB_AS002405 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A048692 | PGDB_C008029 | PGDB_AS001575 | View |
| IC50 | - | = | 0.018 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A076682 | PGDB_C008029 | PGDB_AS000958 | View |