Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C008049
5 activity records1 related patents
2D structure
Cc1nc2c(C3CC(OC(=O)NCc4ccc5c(c4)C(=O)N(C4CCC(=O)NC4=O)C5)C3)cccc2s1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.053 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A024762 | PGDB_C008049 | PGDB_AS002100 | View |
| Kd | - | = | 0.018 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A027276 | PGDB_C008049 | PGDB_AS000522 | View |
| Dmax | - | = | 11 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A044549 | PGDB_C008049 | PGDB_AS000025 | View |
| Dmax | - | = | 54 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A073179 | PGDB_C008049 | PGDB_AS000554 | View |
| IC50 | - | = | 10 | uM | - | — | GSPT1 | CRBN | HEK293 | WO2025043225 | PGDB_A076578 | PGDB_C008049 | PGDB_AS000357 | View |