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Compound
PGDB_C008074
5 activity records1 related patents
2D structure
N#Cc1ccc2scnc2c1[C@H]1C[C@@H](OC(=O)NCc2ccc3c(c2F)C(=O)N(C2CCC(=O)NC2=O)C3)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 72 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A020566 | PGDB_C008074 | PGDB_AS000554 | View |
| Kd | - | = | 0.017 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A020682 | PGDB_C008074 | PGDB_AS000522 | View |
| Dmax | - | = | 23 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A031622 | PGDB_C008074 | PGDB_AS000025 | View |
| IC50 | - | = | 2.8 | uM | - | — | GSPT1 | CRBN | HEK293 | WO2025043225 | PGDB_A033248 | PGDB_C008074 | PGDB_AS000357 | View |
| IC50 | - | = | 0.013 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A065922 | PGDB_C008074 | PGDB_AS002100 | View |