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Compound
PGDB_C008086
5 activity records1 related patents
2D structure
Cc1cnn([C@H]2C[C@H](OC(=O)NCc3ccc4c(c3F)C(=O)N(C3CCC(=O)NC3=O)C4)C2)c1C(F)(F)FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 67 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A009354 | PGDB_C008086 | PGDB_AS000554 | View |
| IC50 | - | = | 10 | uM | - | — | GSPT1 | CRBN | HEK293 | WO2025043225 | PGDB_A026973 | PGDB_C008086 | PGDB_AS000357 | View |
| Dmax | - | = | 3.3 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A028024 | PGDB_C008086 | PGDB_AS000025 | View |
| Kd | - | = | 0.024 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A050471 | PGDB_C008086 | PGDB_AS000522 | View |
| IC50 | - | = | 0.016 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A066095 | PGDB_C008086 | PGDB_AS002100 | View |