Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C008088
5 activity records1 related patents
2D structure
Cc1cc(C(F)(F)F)n([C@H]2C[C@H](OC(=O)NCc3ccc4c(c3F)C(=O)N(C3CCC(=O)NC3=O)C4)C2)n1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.025 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A018344 | PGDB_C008088 | PGDB_AS002100 | View |
| Dmax | - | = | 5.9 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A026636 | PGDB_C008088 | PGDB_AS000025 | View |
| Kd | - | = | 0.027 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A059087 | PGDB_C008088 | PGDB_AS000522 | View |
| IC50 | - | = | 10 | uM | - | — | GSPT1 | CRBN | HEK293 | WO2025043225 | PGDB_A069142 | PGDB_C008088 | PGDB_AS000357 | View |
| Dmax | - | = | 63 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A069392 | PGDB_C008088 | PGDB_AS000554 | View |