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Compound
PGDB_C008102
5 activity records1 related patents
2D structure
Cc1cccc2cnn([C@H]3C[C@H](OC(=O)NCc4ccc5c(c4F)C(=O)N(C4CCC(=O)NC4=O)C5)C3)c12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 75 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A017935 | PGDB_C008102 | PGDB_AS000554 | View |
| IC50 | - | = | 7 | uM | - | — | GSPT1 | CRBN | HEK293 | WO2025043225 | PGDB_A027010 | PGDB_C008102 | PGDB_AS000357 | View |
| IC50 | - | = | 0.011 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A027359 | PGDB_C008102 | PGDB_AS002100 | View |
| Kd | - | = | 0.024 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A048705 | PGDB_C008102 | PGDB_AS000522 | View |
| Dmax | - | = | 15 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A048904 | PGDB_C008102 | PGDB_AS000025 | View |