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Compound
PGDB_C008132
5 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(Cl)cc(CNC(=O)O[C@H]4C[C@@](O)(c5cccnc5OC(F)(F)F)C4)c(F)c3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kd | - | = | 0.16 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A012921 | PGDB_C008132 | PGDB_AS000522 | View |
| Dmax | - | = | 72 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A016415 | PGDB_C008132 | PGDB_AS000554 | View |
| Dmax | - | = | 0.16 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A020995 | PGDB_C008132 | PGDB_AS000025 | View |
| IC50 | - | = | 0.039 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A057850 | PGDB_C008132 | PGDB_AS002100 | View |
| IC50 | - | = | 1 | uM | - | — | GSPT1 | CRBN | HEK293 | WO2025043225 | PGDB_A060821 | PGDB_C008132 | PGDB_AS000357 | View |