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Compound
PGDB_C008165
7 activity records1 related patents
2D structure
Cc1cccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)c1C(F)(F)FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 88.3 | % | Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM | 72 h | GSPT1 | - | HEK293 | IL323841A | PGDB_A021524 | PGDB_C008165 | PGDB_AS002464 | View |
| IC50 | - | = | 34.4 | nM | - | — | GSPT1 | - | HL-60 | IL323841A | PGDB_A029469 | PGDB_C008165 | PGDB_AS002473 | View |
| DC50 | - | = | 118 | nM | - | — | GSPT1 | - | HEK293 | IL323841A | PGDB_A037646 | PGDB_C008165 | PGDB_AS000381 | View |
| IC50 | - | = | 68.3 | nM | - | — | GSPT1 | - | NCI-H1155 | IL323841A | PGDB_A051348 | PGDB_C008165 | PGDB_AS002011 | View |
| IC50 | - | = | 37.8 | nM | - | — | GSPT1 | - | HL-60 | IL323841A | PGDB_A060517 | PGDB_C008165 | PGDB_AS000799 | View |
| IC50 | - | = | 60.2 | nM | - | — | GSPT1 | - | NCI-H1155 | IL323841A | PGDB_A065661 | PGDB_C008165 | PGDB_AS000925 | View |
| EC50 | - | = | 123 | nM | - | — | GSPT1 | - | HEK293 | IL323841A | PGDB_A069961 | PGDB_C008165 | PGDB_AS002492 | View |