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Compound
PGDB_C024222
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(NN4CC5CCC(C4)N5CC4=C(c5ccc(Cl)cc5)CCOC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 40-50 | % | 10 nM | 96 h | IKZF3 | - | CFPAC-1 | WO2025162225A1 | PGDB_A021763 | PGDB_C024222 | PGDB_AS000245 | View |
| % Inhibition | - | = | 30-40 | % | 10 nM | 96 h | IKZF3 | - | H196 | WO2025162225A1 | PGDB_A024273 | PGDB_C024222 | PGDB_AS001140 | View |
| % Inhibition | - | = | 80-100 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A027954 | PGDB_C024222 | PGDB_AS002540 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A028065 | PGDB_C024222 | PGDB_AS002133 | View |
| % Inhibition | - | = | 30-40 | % | 10 nM | 96 h | IKZF3 | - | A375 | WO2025162225A1 | PGDB_A036113 | PGDB_C024222 | PGDB_AS001349 | View |
| % Inhibition | - | = | 40-50 | % | 500 nM | 96 h | IKZF3 | - | A375 | WO2025162225A1 | PGDB_A059664 | PGDB_C024222 | PGDB_AS000568 | View |
| % Inhibition | - | = | 60-70 | % | 500 nM | 96 h | IKZF3 | - | CFPAC-1 | WO2025162225A1 | PGDB_A065052 | PGDB_C024222 | PGDB_AS000857 | View |
| % Inhibition | - | = | 40-50 | % | 500 nM | 96 h | IKZF3 | - | H196 | WO2025162225A1 | PGDB_A068220 | PGDB_C024222 | PGDB_AS000866 | View |