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Compound
PGDB_C027547
4 activity records2 related patents
2D structure
O=C1CCC(c2c(F)cc(N3CC(Nc4nnc(-c5ccc(OC(F)(F)F)cc5)o4)C3)cc2F)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | > | 80 | % | 30 uM | 24 h | - | - | HEK293 | WO2024092039 | PGDB_A010580 | PGDB_C027547 | PGDB_AS002575 | View |
| Dmax | - | > | 80 | % | 30 uM | 24 h | CDK2 | - | HEK293 | WO2025224262A1 | PGDB_A025560 | PGDB_C027547 | PGDB_AS001415 | View |
| Ki | - | <= | 0.1 | uM | - | — | CRBN | CRBN | - | WO2025224262A1 | PGDB_A029248 | PGDB_C027547 | PGDB_AS001844 | View |
| Ki | - | <= | 0.1 | uM | - | — | - | - | - | WO2024092039 | PGDB_A033560 | PGDB_C027547 | PGDB_AS001899 | View |