PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2026062066A1

AssigneeForx Therapeutics AG

TitleCompounds inducing parg degradation

Family IDunresolved_family_WO2026062066A1

Family members1

Filing year2025

Publication date2026-03-26

JurisdictionWO

Compounds43

Activity records106

Assays6

Activity compounds and values

Activity records

104 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
EC50	-	=	0.257	uM	-	—	PARG	-	MDA-MB-436	PGDB_A000425	PGDB_C030624	PGDB_AS001599	View
IC50	-	=	0.114	uM	-	—	PARG	-	-	PGDB_A000487	PGDB_C025567	PGDB_AS002282	View
EC50	-	=	0.633	uM	-	—	PARG	-	NCIH-460	PGDB_A000600	PGDB_C030613	PGDB_AS002426	View
IC50	-	=	0.079	uM	-	—	PARG	-	-	PGDB_A000839	PGDB_C030642	PGDB_AS002282	View
IC50	-	=	0.148	uM	-	—	PARG	-	-	PGDB_A000848	PGDB_C030643	PGDB_AS002282	View
IC50	-	=	0.144	uM	-	—	PARG	-	-	PGDB_A000894	PGDB_C030646	PGDB_AS002282	View
EC50	-	>	20	uM	-	—	PARG	-	U2OS	PGDB_A000896	PGDB_C030607	PGDB_AS002468	View
EC50	-	>	20	uM	-	—	PARG	-	U2OS	PGDB_A000965	PGDB_C030613	PGDB_AS002468	View
EC50	-	=	1.25	uM	-	—	PARG	-	NCIH-460	PGDB_A001019	PGDB_C030622	PGDB_AS002426	View
IC50	-	=	5.5	uM	-	—	PARG	-	-	PGDB_A001164	PGDB_C030630	PGDB_AS002282	View
IC50	-	=	0.716	uM	-	—	PARG	-	-	PGDB_A001205	PGDB_C030648	PGDB_AS002282	View
EC50	-	>	20	uM	-	—	PARG	-	U2OS	PGDB_A001273	PGDB_C030624	PGDB_AS002468	View
IC50	-	=	16	uM	-	—	PARG	-	-	PGDB_A002057	PGDB_C030633	PGDB_AS002282	View
IC50	-	=	1	uM	-	—	PARG	-	-	PGDB_A002096	PGDB_C030621	PGDB_AS002282	View
IC50	-	=	0.1	uM	-	—	PARG	-	-	PGDB_A002239	PGDB_C030635	PGDB_AS002282	View
IC50	-	=	0.146	uM	-	—	PARG	-	-	PGDB_A002347	PGDB_C030607	PGDB_AS002282	View
EC50	-	=	0.07	uM	-	—	PARG	-	NCIH-460	PGDB_A002392	PGDB_C030612	PGDB_AS002426	View
EC50	-	>	20	uM	-	—	PARG	-	NCIH-460	PGDB_A002572	PGDB_C030606	PGDB_AS002426	View
EC50	-	=	0.18	uM	-	—	PARG	-	MDA-MB-436	PGDB_A002662	PGDB_C030612	PGDB_AS001599	View
EC50	-	>	18.6	uM	-	—	PARG	-	U2OS	PGDB_A002693	PGDB_C030611	PGDB_AS002468	View

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