PatGlueDB | Molecular Glue Patent Bioactivity Database

Target summary

Target IDPGDB_T000010

NameMYC

Gene symbolMYC

Protein nameMyc proto-oncogene protein

UniProt IDP01106

Roledegradation_target | neo_substrate | primary_target

Compounds155

Activity records560

Assays17

Patents3

Activity compounds and values

Activity records

560 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
IC50	-	=	0.863	uM	-	—	MYC	-	A2780	CN120040371B	PGDB_A007074	PGDB_C007014	PGDB_AS001017	View
IC50	-	=	0.472	uM	-	—	MYC	-	Daudi	CN120040371B	PGDB_A007203	PGDB_C007041	PGDB_AS000270	View
% Degradation	-	=	74.88	%	7.5 uM	9 h	MYC	-	Daudi	CN120040371B	PGDB_A007457	PGDB_C007049	PGDB_AS000260	View
IC50	-	=	6.392	uM	-	—	MYC	-	SJSA-1	CN120040371B	PGDB_A007470	PGDB_C006985	PGDB_AS000442	View
IC50	-	=	0.372	uM	-	—	MYC	-	Daudi	CN120040371B	PGDB_A007671	PGDB_C007021	PGDB_AS000270	View
% Degradation	-	=	57	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A007749	PGDB_C000579	PGDB_AS002563	View
IC50	-	=	0.482	uM	-	—	MYC	-	MV-4-11	CN120040371B	PGDB_A007826	PGDB_C006990	PGDB_AS001813	View
% Degradation	-	=	15.18	%	3 uM	12 h	MYC	-	Daudi	CN120040371B	PGDB_A007915	PGDB_C007025	PGDB_AS000007	View
% Degradation	-	=	95.37	%	7.5 uM	12 h	MYC	-	Daudi	CN120040371B	PGDB_A007944	PGDB_C007044	PGDB_AS000998	View
IC50	-	=	28.472	uM	-	—	MYC	-	MV-4-11	CN120040371B	PGDB_A007947	PGDB_C007043	PGDB_AS001813	View
IC50	-	=	6.382	uM	-	—	MYC	-	MV-4-11	CN120040371B	PGDB_A008207	PGDB_C007014	PGDB_AS001813	View
IC50	-	=	8.482	uM	-	—	MYC	-	COLO 320DM	CN120040371B	PGDB_A008250	PGDB_C006996	PGDB_AS001884	View
IC50	-	=	8.612	uM	-	—	MYC	-	MV-4-11	CN120040371B	PGDB_A008288	PGDB_C007040	PGDB_AS001813	View
IC50	-	=	6.382	uM	-	—	MYC	-	MV-4-11	CN120040371B	PGDB_A008583	PGDB_C007062	PGDB_AS001813	View
IC50	-	=	5.382	uM	-	—	MYC	-	MV-4-11	CN120040371B	PGDB_A008751	PGDB_C006999	PGDB_AS001813	View
% Degradation	-	=	89	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A008939	PGDB_C000621	PGDB_AS002563	View
IC50	-	=	0.954	uM	-	—	MYC	-	A2780	CN120040371B	PGDB_A009065	PGDB_C007010	PGDB_AS001017	View
IC50	-	=	18.143	uM	-	—	MYC	-	SJSA-1	CN120040371B	PGDB_A009471	PGDB_C006992	PGDB_AS000442	View
% Degradation	-	=	83	%	10 nM	24 h	MYC	-	HL-60	WO2023116835A1	PGDB_A009657	PGDB_C000540	PGDB_AS002563	View
IC50	-	=	6.831	uM	-	—	MYC	-	MV-4-11	CN120040371B	PGDB_A009694	PGDB_C007045	PGDB_AS001813	View

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