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Compound
PGDB_C000379
7 activity records1 related patents
2D structure
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)COc1cccc3c1C(=O)N(C1CCC(=O)NC1=O)C3=O)c1nnc(C)n1-2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | > | 2000 | nM | - | — | BRD4/GSPT1 | - | Oci-AML3 | CN117756818A | PGDB_A019468 | PGDB_C000379 | PGDB_AS002081 | View |
| IC50 | - | = | 1000-2000 | nM | - | — | - | - | THP-1 | CN117756818A | PGDB_A026371 | PGDB_C000379 | PGDB_AS000638 | View |
| IC50 | - | = | 100-1000 | nM | - | — | BRD4/GSPT1 | - | NB4 | CN117756818A | PGDB_A034720 | PGDB_C000379 | PGDB_AS000935 | View |
| % Degradation | - | = | 70-90 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A035892 | PGDB_C000379 | PGDB_AS002573 | View |
| % Degradation | - | < | 30 | % | - | - | - | - | MOLM-13 | CN117756818A | PGDB_A060357 | PGDB_C000379 | PGDB_AS000622 | View |
| IC50 | - | = | 1000-2000 | nM | - | — | BRD4/GSPT1 | - | HL-60 | CN117756818A | PGDB_A062394 | PGDB_C000379 | PGDB_AS001357 | View |
| IC50 | - | = | 100-1000 | nM | - | — | - | - | MOLM-13 | CN117756818A | PGDB_A077375 | PGDB_C000379 | PGDB_AS001583 | View |