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Compound
PGDB_C001327
9 activity records2 related patents
2D structure
O=C1CCC(N2Cc3cc(C(=O)c4cc5cc(F)ccc5[nH]4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GI50 | - | <= | 0.1 | uM | - | — | GSPT1 | - | MM.1S | WO2025110699A1 | PGDB_A009373 | PGDB_C001327 | PGDB_AS002497 | View |
| GI50 | - | <= | 0.1 | nM | - | — | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A026936 | PGDB_C001327 | PGDB_AS000013 | View |
| % Degradation | - | = | 90-100 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A045914 | PGDB_C001327 | PGDB_AS001067 | View |
| % Degradation | - | = | 90-100 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A053484 | PGDB_C001327 | PGDB_AS000601 | View |
| % Degradation | - | = | 90-100 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A055226 | PGDB_C001327 | PGDB_AS001008 | View |
| GI50 | - | <= | 0.1 | uM | - | — | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A065943 | PGDB_C001327 | PGDB_AS001887 | View |
| % Degradation | - | = | 90-100 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A067672 | PGDB_C001327 | PGDB_AS002288 | View |
| % Degradation | - | = | 90-100 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A068502 | PGDB_C001327 | PGDB_AS001994 | View |
| % Degradation | - | = | 90-100 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A077239 | PGDB_C001327 | PGDB_AS001448 | View |