PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

55 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetGSPT1

E3Not specified

Cell lineJurkat

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

55 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A007052	PGDB_C001322	PGDB_AS001994	View
% Degradation	-	=	70-90	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A007788	PGDB_C001345	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A009427	PGDB_C001330	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A015555	PGDB_C001310	PGDB_AS001994	View
% Degradation	-	=	70-90	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A015947	PGDB_C001320	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A017937	PGDB_C001323	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A018737	PGDB_C001360	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A019743	PGDB_C001351	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A020282	PGDB_C001341	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A020590	PGDB_C001349	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A020780	PGDB_C001353	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A022451	PGDB_C001303	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A023553	PGDB_C001336	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A025593	PGDB_C001302	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A025834	PGDB_C001307	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A027004	PGDB_C001344	PGDB_AS001994	View
% Degradation	-	=	70-90	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A027338	PGDB_C001342	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A029399	PGDB_C001318	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A031653	PGDB_C001354	PGDB_AS001994	View
% Degradation	-	=	90-100	%	10 uM	24 h	GSPT1	-	Jurkat	WO2025110699A1	PGDB_A032382	PGDB_C001358	PGDB_AS001994	View

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