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Compound
PGDB_C001343
9 activity records2 related patents
2D structure
O=C1CCC(N2Cc3cc(C(=O)c4ccc(Br)cc4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 70-90 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A008905 | PGDB_C001343 | PGDB_AS002288 | View |
| % Degradation | - | = | 70-90 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A019288 | PGDB_C001343 | PGDB_AS001448 | View |
| GI50 | - | = | 1-10 | uM | - | — | GSPT1 | - | MM.1S | WO2025110699A1 | PGDB_A038664 | PGDB_C001343 | PGDB_AS002497 | View |
| % Degradation | - | = | 70-90 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A042694 | PGDB_C001343 | PGDB_AS001067 | View |
| % Degradation | - | = | 70-90 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A053881 | PGDB_C001343 | PGDB_AS001008 | View |
| GI50 | - | <= | 0.1 | nM | - | — | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A054295 | PGDB_C001343 | PGDB_AS000013 | View |
| % Degradation | - | = | 70-90 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A065145 | PGDB_C001343 | PGDB_AS001994 | View |
| % Degradation | - | = | 70-90 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A070342 | PGDB_C001343 | PGDB_AS000601 | View |
| GI50 | - | <= | 0.1 | uM | - | — | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A075470 | PGDB_C001343 | PGDB_AS001887 | View |