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Compound
PGDB_C001353
8 activity records2 related patents
2D structure
Cc1cccc(C(=O)c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 90-100 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A020780 | PGDB_C001353 | PGDB_AS001994 | View |
| % Degradation | - | = | 90-100 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A042917 | PGDB_C001353 | PGDB_AS000601 | View |
| % Degradation | - | = | 90-100 | % | 1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A043911 | PGDB_C001353 | PGDB_AS001008 | View |
| GI50 | - | <= | 0.1 | nM | - | — | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A051676 | PGDB_C001353 | PGDB_AS000013 | View |
| % Degradation | - | = | 90-100 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A069599 | PGDB_C001353 | PGDB_AS001067 | View |
| GI50 | - | <= | 0.1 | uM | - | — | GSPT1 | - | Jurkat | WO2025110699A1 | PGDB_A074284 | PGDB_C001353 | PGDB_AS001887 | View |
| % Degradation | - | = | 90-100 | % | 10 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A076558 | PGDB_C001353 | PGDB_AS001448 | View |
| % Degradation | - | = | 90-100 | % | 0.1 uM | 24 h | GSPT1 | - | Jurkat | KR20250075510A | PGDB_A077797 | PGDB_C001353 | PGDB_AS002288 | View |