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Compound
PGDB_C002505
10 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CC4CCN(C(=O)c5ccccc5-c5ccc(Cl)cc5)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 10-50 | nM | - | — | - | - | MV-4-11 | WO2024032689A1 | PGDB_A015577 | PGDB_C002505 | PGDB_AS000885 | View |
| IC50 | - | = | 10-50 | nM | - | — | - | - | Kasumi-1 | WO2024032689A1 | PGDB_A016439 | PGDB_C002505 | PGDB_AS001291 | View |
| IC50 | - | = | 0.52 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A017222 | PGDB_C002505 | PGDB_AS000095 | View |
| IC50 | - | = | 5-10 | nM | - | — | - | - | CCRF-CEM | WO2024032689A1 | PGDB_A019083 | PGDB_C002505 | PGDB_AS001396 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A026343 | PGDB_C002505 | PGDB_AS002239 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A033449 | PGDB_C002505 | PGDB_AS000176 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A046293 | PGDB_C002505 | PGDB_AS000668 | View |
| IC50 | - | = | 10-50 | nM | - | — | - | - | Mino | WO2024032689A1 | PGDB_A054174 | PGDB_C002505 | PGDB_AS001319 | View |
| IC50 | - | = | 100-500 | nM | - | — | - | - | Daudi | WO2024032689A1 | PGDB_A066428 | PGDB_C002505 | PGDB_AS002481 | View |
| IC50 | - | = | 10-50 | nM | - | — | - | - | MM.1S | WO2024032689A1 | PGDB_A070016 | PGDB_C002505 | PGDB_AS001703 | View |