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Compound
PGDB_C002806
9 activity records2 related patents
2D structure
O=C1CCC(N2Cc3cc(NC(=O)c4ccccc4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 65.5 | % | 1 uM | - | CSNK1A1 | - | - | WO2024059107A1 | PGDB_A019793 | PGDB_C002806 | PGDB_AS000685 | View |
| % Degradation | - | = | 52.1 | % | 100 nM | - | IKZF1 | - | - | WO2024059107A1 | PGDB_A032866 | PGDB_C002806 | PGDB_AS000707 | View |
| % Degradation | - | = | 0 | % | 100 nM | - | GSPT1 | - | - | WO2024059107A1 | PGDB_A035267 | PGDB_C002806 | PGDB_AS002431 | View |
| % Degradation | - | = | 91.9 | % | 1 uM | - | IKZF2 | - | - | WO2024059107A1 | PGDB_A045968 | PGDB_C002806 | PGDB_AS000892 | View |
| % Degradation | - | = | 85.4 | % | 1 uM | - | IKZF1 | - | - | WO2024059107A1 | PGDB_A050601 | PGDB_C002806 | PGDB_AS000768 | View |
| % Degradation | - | = | 38.7 | % | 100 nM | - | CSNK1A1 | - | - | WO2024059107A1 | PGDB_A060192 | PGDB_C002806 | PGDB_AS000209 | View |
| IC50 | - | < | 1 | uM | - | — | - | - | - | WO2024015618A2 | PGDB_A072941 | PGDB_C002806 | PGDB_AS000636 | View |
| % Degradation | - | = | 77.4 | % | 100 nM | - | IKZF2 | - | - | WO2024059107A1 | PGDB_A074521 | PGDB_C002806 | PGDB_AS001414 | View |
| % Degradation | - | = | 14.1 | % | 1 uM | - | GSPT1 | - | - | WO2024059107A1 | PGDB_A076869 | PGDB_C002806 | PGDB_AS001974 | View |