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Compound
PGDB_C002807
10 activity records2 related patents
2D structure
CC(=O)Nc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 4.4 | % | 100 nM | - | IKZF1 | - | - | WO2024059107A1 | PGDB_A007445 | PGDB_C002807 | PGDB_AS000707 | View |
| % Degradation | - | = | 9.9 | % | 100 nM | - | GSPT1 | - | - | WO2024059107A1 | PGDB_A010433 | PGDB_C002807 | PGDB_AS002431 | View |
| % Degradation | - | = | 25.4 | % | 1 uM | - | CSNK1A1 | - | - | WO2024059107A1 | PGDB_A037982 | PGDB_C002807 | PGDB_AS000685 | View |
| % Degradation | - | = | 12 | % | 100 nM | - | CSNK1A1 | - | - | WO2024059107A1 | PGDB_A038385 | PGDB_C002807 | PGDB_AS000209 | View |
| % Degradation | - | = | 8.6 | % | 1 uM | - | GSPT1 | - | - | WO2024059107A1 | PGDB_A039803 | PGDB_C002807 | PGDB_AS001974 | View |
| % Degradation | - | = | 10.9 | % | 1 uM | - | IKZF1 | - | - | WO2024059107A1 | PGDB_A042082 | PGDB_C002807 | PGDB_AS000768 | View |
| IC50 | - | = | 0.00000143168 | M | - | — | - | - | - | AU2020404956A1 | PGDB_A048433 | PGDB_C002807 | PGDB_AS000835 | View |
| % Degradation | - | = | 16.6 | % | 100 nM | - | IKZF2 | - | - | WO2024059107A1 | PGDB_A048965 | PGDB_C002807 | PGDB_AS001414 | View |
| EC50 | - | = | 0.000000186 | M | - | — | - | - | - | AU2020404956A1 | PGDB_A049196 | PGDB_C002807 | PGDB_AS002366 | View |
| % Degradation | - | = | 48.5 | % | 1 uM | - | IKZF2 | - | - | WO2024059107A1 | PGDB_A061587 | PGDB_C002807 | PGDB_AS000892 | View |