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Compound
PGDB_C006583
5 activity records1 related patents
2D structure
CC(C)c1cnn2c(NCc3cnc4ccccn34)cc(NC[C@H]3CCNC[C@@H]3O)nc12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 14.8 | nM | - | — | CDK12 | - | A673 | CN114929708B | PGDB_A029813 | PGDB_C006583 | PGDB_AS002570 | View |
| IC50 | - | = | 96 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A050419 | PGDB_C006583 | PGDB_AS001268 | View |
| Selectivity index | CDK7 / CDK12 | = | 1.9 | fold | - | — | - | - | - | CN114929708B | PGDB_A068294 | PGDB_C006583 | PGDB_AS002236 | View |
| IC50 | - | = | 179 | nM | - | — | CDK7 | - | - | CN114929708B | PGDB_A070404 | PGDB_C006583 | PGDB_AS002150 | View |
| IC50 | - | = | 96 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A075209 | PGDB_C006583 | PGDB_AS001187 | View |