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Compound
PGDB_C006587
5 activity records1 related patents
2D structure
CC(C)c1cnn2c(NCc3cc4ccccc4o3)cc(NC[C@H]3CCNC[C@@H]3O)nc12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selectivity index | CDK7 / CDK12 | = | 0.2 | fold | - | — | - | - | - | CN114929708B | PGDB_A027553 | PGDB_C006587 | PGDB_AS002236 | View |
| IC50 | - | = | 115.5 | nM | - | — | CDK12 | - | A673 | CN114929708B | PGDB_A041408 | PGDB_C006587 | PGDB_AS002570 | View |
| IC50 | - | = | 540 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A059502 | PGDB_C006587 | PGDB_AS001187 | View |
| IC50 | - | = | 82 | nM | - | — | CDK7 | - | - | CN114929708B | PGDB_A065418 | PGDB_C006587 | PGDB_AS002150 | View |
| IC50 | - | = | 540 | nM | - | — | CDK12 | - | - | CN114929708B | PGDB_A072641 | PGDB_C006587 | PGDB_AS001268 | View |