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Compound
PGDB_C007937
7 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(CNC(=O)OCc4nc5c(s4)CC(c4ccccc4)CC5)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 29 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A025075 | PGDB_C007937 | PGDB_AS001468 | View |
| IC50 | - | = | 0.36 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A035166 | PGDB_C007937 | PGDB_AS002528 | View |
| Dmax | - | = | 28 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A040669 | PGDB_C007937 | PGDB_AS002435 | View |
| IC50 | - | = | 0.11 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A059902 | PGDB_C007937 | PGDB_AS001908 | View |
| IC50 | - | = | 1.1 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A060090 | PGDB_C007937 | PGDB_AS002309 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A060880 | PGDB_C007937 | PGDB_AS002153 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A067817 | PGDB_C007937 | PGDB_AS002070 | View |