Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C008020
7 activity records1 related patents
2D structure
Cc1ccc(C2CC(OC(=O)NCc3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4)C2)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A021709 | PGDB_C008020 | PGDB_AS002508 | View |
| IC50 | - | = | 0.15 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A022749 | PGDB_C008020 | PGDB_AS000366 | View |
| IC50 | - | = | 0.19 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A030823 | PGDB_C008020 | PGDB_AS002405 | View |
| IC50 | - | = | 31 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A041975 | PGDB_C008020 | PGDB_AS001575 | View |
| Dmax | - | = | 24 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A055285 | PGDB_C008020 | PGDB_AS002240 | View |
| Dmax | - | = | 20 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A062489 | PGDB_C008020 | PGDB_AS000735 | View |
| IC50 | - | = | 0.043 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A072631 | PGDB_C008020 | PGDB_AS000958 | View |