Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C011629
7 activity records1 related patents
2D structure
CCn1c(C2CC(C#C[C@H](C)N3CCOCC3)=CN=C2C(C)OC)c2c3cc(ccc31)-c1csc(n1)CC(NC(=O)C1CC1C)C(=O)N1NC(C(=O)OCC(C)(C)C2)C2CC1C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A011262 | PGDB_C011629 | PGDB_AS001818 | View |
| IC50 | - | = | 1-10 | nM | - | — | - | - | AsPC-1 | WO2025214350A1 | PGDB_A019965 | PGDB_C011629 | PGDB_AS001410 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A022888 | PGDB_C011629 | PGDB_AS000307 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A032058 | PGDB_C011629 | PGDB_AS000928 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A068341 | PGDB_C011629 | PGDB_AS000791 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A072428 | PGDB_C011629 | PGDB_AS002054 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | NCI-H358 | WO2025214350A1 | PGDB_A074239 | PGDB_C011629 | PGDB_AS001442 | View |