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Compound
PGDB_C029477
8 activity records2 related patents
2D structure
O=C1CCC(c2cccc(-c3ccc(-n4cccc(OC(F)F)c4=O)cc3)c2Cl)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 98.28 | % | Concentration series: 10 uM, 1 uM | - | VAV1 | - | - | WO2026051943A1 | PGDB_A000133 | PGDB_C029477 | PGDB_AS000777 | View |
| IC50 | - | = | 0.23 | nM | - | — | VAV1 | - | pan-T | WO2026051943A1 | PGDB_A000245 | PGDB_C029477 | PGDB_AS000112 | View |
| DC50 | - | = | 5.357 | nM | - | — | VAV1 | - | - | WO2026051943A1 | PGDB_A001712 | PGDB_C029477 | PGDB_AS001440 | View |
| DC50 | - | <= | 20 | nM | - | — | VAV1 | - | primary_human_blood | WO2026114367A1 | PGDB_A003326 | PGDB_C029477 | PGDB_AS001692 | View |
| IC50 | - | <= | 1 | nM | - | — | VAV1 | - | primary T cells | WO2026114367A1 | PGDB_A004429 | PGDB_C029477 | PGDB_AS000754 | View |
| DC50 | - | <= | 20 | nM | - | — | VAV1 | - | - | WO2026114367A1 | PGDB_A079484 | PGDB_C029477 | PGDB_AS000190 | View |
| IC50 | - | <= | 1 | nM | - | — | VAV1 | - | primaryT | WO2026114367A1 | PGDB_A079855 | PGDB_C029477 | PGDB_AS000152 | View |
| IC50 | - | <= | 1 | nM | - | — | VAV1 | - | primaryT | WO2026114367A1 | PGDB_A080990 | PGDB_C029477 | PGDB_AS002534 | View |