PatGlueDB | Molecular Glue Patent Bioactivity Database

Target summary

Target IDPGDB_T000055

NameSMARCA2

Gene symbolSMARCA2

Protein nameSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

UniProt IDP51531

Roledegradation_target | primary_target

Compounds1,173

Activity records2,617

Assays10

Patents6

Activity compounds and values

Activity records

2,617 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
Dmax	-	=	82.64	%	-	-	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000031	PGDB_C032405	PGDB_AS002073	View
Dmax	-	=	84.53	%	-	-	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000053	PGDB_C032432	PGDB_AS002073	View
Dmax	-	=	88.35	%	-	-	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000057	PGDB_C032399	PGDB_AS002073	View
Dmax	-	=	90.47	%	-	-	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000069	PGDB_C032311	PGDB_AS002073	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA2	-	MV-4-11	WO2026061475A1	PGDB_A000083	PGDB_C030288	PGDB_AS002335	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA2	-	MV-4-11	WO2026061475A1	PGDB_A000097	PGDB_C030300	PGDB_AS002335	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA2	-	MV-4-11	WO2026061475A1	PGDB_A000118	PGDB_C030420	PGDB_AS002335	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA2	-	MV-4-11	WO2026061475A1	PGDB_A000129	PGDB_C030588	PGDB_AS002335	View
DC50	-	=	4.88	nM	-	—	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000162	PGDB_C032383	PGDB_AS002506	View
Dmax	-	=	97.57	%	-	-	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000171	PGDB_C032416	PGDB_AS002073	View
DC50	-	=	0.9	nM	-	—	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000241	PGDB_C032416	PGDB_AS002506	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA2	-	MV-4-11	WO2026061475A1	PGDB_A000248	PGDB_C030578	PGDB_AS002335	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA2	-	MV-4-11	WO2026061475A1	PGDB_A000287	PGDB_C030460	PGDB_AS002335	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA2	-	MV-4-11	WO2026061475A1	PGDB_A000291	PGDB_C030480	PGDB_AS002335	View
DC50	-	=	18.3	nM	-	—	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000330	PGDB_C032426	PGDB_AS002506	View
DC50	-	=	4.82	nM	-	—	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000341	PGDB_C032334	PGDB_AS002506	View
DC50	-	=	8.78	nM	-	—	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000351	PGDB_C032364	PGDB_AS002506	View
Dmax	-	=	96.27	%	-	-	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000366	PGDB_C032420	PGDB_AS002073	View
DC50	-	=	3.24	nM	-	—	SMARCA2	-	Calu-6	WO2026128580A1	PGDB_A000446	PGDB_C032367	PGDB_AS002506	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA2	-	MV-4-11	WO2026061475A1	PGDB_A000509	PGDB_C030418	PGDB_AS002335	View

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